Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells

Myeloid-derived suppressor cells (MDSCs) are immune suppressive cells that are hallmarks of human cancer. MDSCs inhibit cytotoxic T lymphocytes (CTLs) and NK cell functions to promote tumor immune escape and progression, and therefore are considered key targets in cancer immunotherapy. Recent studie...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Liu, Feiyan, Li, Xia, Lu, Chunwan, Bai, Aiping, Bielawski, Jacek, Bielawska, Alicja, Marshall, Brendan, Schoenlein, Patricia V., Lebedyeva, Iryna O., Liu, Kebin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper: Immunology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356634/
https://ncbi.nlm.nih.gov/pubmed/27880732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13438
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller