C16-Ceramide Analog Combined with Pc 4 Photodynamic Therapy Evokes Enhanced Total Ceramide Accumulation, Promotion of DEVDase Activation in the Absence of Apoptosis, and Augmented Overall Cell Killing

Because of the failure of single modality approaches, combination therapy for cancer treatment is a promising alternative. Sphingolipid analogs, with or without anticancer drugs, can improve tumor response. C16-pyridinium ceramide analog LCL30, was used in combination with photodynamic therapy (PDT)...

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Detalhes bibliográficos
Main Authors: Separovic, Duska, Saad, Ziad H., Edwin, Ethan A., Bielawski, Jacek, Pierce, Jason S., Buren, Eric Van, Bielawska, Alicja
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066794/
https://ncbi.nlm.nih.gov/pubmed/21490809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/713867
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