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Synthesis, NMR characterization and divergent biological actions of 2′-hydroxy-ceramide/dihydroceramide stereoisomers in MCF7 cells
A straightforward method for the simultaneous preparation of (2S, 3R, 2′R)- and (2S, 3R, 2′S)-2′-hydroxy-ceramides (2′-OHCer) from (2S, 3R)-sphingosine acetonide precursors and racemic mixtures of 2-hydroxy fatty acids (2-OHFAs) is described. The obtained 2′-OH-C4-, -C6-, -C12-, -C16-Cer and 2′-OH-C...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956829/ https://ncbi.nlm.nih.gov/pubmed/20851613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.08.050 |
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