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Novel Analogs of D-e-MAPP and B13. Part 1. Synthesis and Evaluation as Potential Anticancer Agents
A series of novel isosteric analogs of the ceramidase inhibitors, (1S, 2R)-N-myristoylamino-phenylpropanol-1 (D-e-MAPP) and (1R, 2R)-N-myristoylamino-4′-nitro-phenylpropandiol-1, 3 (B13), with modified targeting and physicochemical properties were designed, synthesized, and evaluated as potential an...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2287182/ https://ncbi.nlm.nih.gov/pubmed/17869115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.08.033 |
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