Novel Analogs of D-e-MAPP and B13. Part 2. Signature Effects on Bioactive Sphingolipids

Novel isosteric analogs of the ceramidase inhibitors (1S, 2R)-N-myristoylamino-phenylpropanol-1 (D-e-MAPP) and (1R, 2R)-N-myristoylamino-4′-nitro-phenylpropandiol-1, 3 (B13) with modified targeting and physicochemical properties were developed and evaluated for their effects on endogenous bioactive...

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Autors principals: Bielawska, Alicja, Bielawski, Jacek, Szulc, Zdzislaw M., Mayroo, Nalini, Liu, Xiang, Bai, AiPing, Elojeimy, Saeed, Rembiesa, Barbara, Pierce, Jason, Norris, James S., Hannun, Yusuf A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268750/
https://ncbi.nlm.nih.gov/pubmed/17881234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.08.032
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