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Involvement Of The Dihydroceramide Desaturase In Cell Cycle Progression In Human Neuroblastoma Cells

The role of dihydroceramide desaturase as a key enzyme in the de-novo pathway of ceramide generation was investigated in human neuroblastoma cells (SMS-KCNR). A novel assay using water soluble analogs of dihydroceramide, dihydroceramidoids (D-e-dhCCPS analogs) was used to measure desaturase activity...

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Detalhes bibliográficos
Main Authors: Kraveka, Jacqueline M., Li, Li, Szulc, Zdzislaw M., Bielawski, Jacek, Ogretmen, Besim, Hannun, Yusuf A., Obeid, Lina M., Bielawska, Alicja
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2084375/
https://ncbi.nlm.nih.gov/pubmed/17283068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M700647200
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