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Notch Inhibition Enhances Cardiac Reprogramming by Increasing MEF2C Transcriptional Activity
Conversion of fibroblasts into functional cardiomyocytes represents a potential means of restoring cardiac function after myocardial infarction, but so far this process remains inefficient and little is known about its molecular mechanisms. Here we show that DAPT, a classical Notch inhibitor, enhanc...
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| Vydáno v: | Stem Cell Reports |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Elsevier
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355682/ https://ncbi.nlm.nih.gov/pubmed/28262548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.01.025 |
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