ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression

Direct reprogramming of fibroblasts to cardiomyocytes represents a potential means of restoring cardiac function following myocardial injury. AKT1 in the presence of four cardiogenic transcription factors, GATA4, HAND2, MEF2C, and TBX5 (AGHMT), efficiently induces the cardiac gene program in mouse e...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Zhou, Huanyu, Morales, Maria Gabriela, Hashimoto, Hisayuki, Dickson, Matthew E., Song, Kunhua, Ye, Wenduo, Kim, Min S., Niederstrasser, Hanspeter, Wang, Zhaoning, Chen, Beibei, Posner, Bruce A., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666675/
https://ncbi.nlm.nih.gov/pubmed/28982760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.305482.117
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