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Akt1/protein kinase B enhances transcriptional reprogramming of fibroblasts to functional cardiomyocytes

Conversion of fibroblasts to functional cardiomyocytes represents a potential approach for restoring cardiac function after myocardial injury, but the technique thus far has been slow and inefficient. To improve the efficiency of reprogramming fibroblasts to cardiac-like myocytes (iCMs) by cardiac t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhou, Huanyu, Dickson, Matthew E., Kim, Min Soo, Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586885/
https://ncbi.nlm.nih.gov/pubmed/26354121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516237112
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