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Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors
Various combinations of cardiogenic transcription factors, including Gata4 (G), Hand2 (H), Mef2c (M) and Tbx5 (T), can reprogram fibroblasts into induced cardiac-like myocytes (iCLMs) in vitro and in vivo. Given that optimal cardiac function relies on distinct yet functionally interconnected atrial,...
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| Publicado no: | Development |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4302916/ https://ncbi.nlm.nih.gov/pubmed/25344074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.114025 |
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