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TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling

The heart responds to injury and chronic pressure overload by pathologic growth and remodeling, which frequently result in heart failure and sudden death. Calcium-dependent signaling pathways promote cardiac growth and associated changes in gene expression in response to stress. The calcium/calmodul...

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Bibliografiske detaljer
Main Authors: Kuwahara, Koichiro, Wang, Yanggan, McAnally, John, Richardson, James A., Bassel-Duby, Rhonda, Hill, Joseph A., Olson, Eric N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635163/
https://ncbi.nlm.nih.gov/pubmed/17099778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27702
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