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Requirement of protein kinase D1 for pathological cardiac remodeling
The adult heart responds to biomechanical stress and neurohormonal signaling by hypertrophic growth, accompanied by fibrosis, diminished pump function, and activation of a fetal gene program. Class II histone deacetylases (HDACs) suppress stress-dependent remodeling of the heart via their associatio...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268584/ https://ncbi.nlm.nih.gov/pubmed/18287012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712265105 |
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