Requirement of protein kinase D1 for pathological cardiac remodeling

The adult heart responds to biomechanical stress and neurohormonal signaling by hypertrophic growth, accompanied by fibrosis, diminished pump function, and activation of a fetal gene program. Class II histone deacetylases (HDACs) suppress stress-dependent remodeling of the heart via their associatio...

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Hlavní autoři: Fielitz, Jens, Kim, Mi-Sung, Shelton, John M., Qi, Xiaoxia, Hill, Joseph A., Richardson, James A., Bassel-Duby, Rhonda, Olson, Eric N.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268584/
https://ncbi.nlm.nih.gov/pubmed/18287012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712265105
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