Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response

The highly pathogenic avian influenza (HPAI) H5N1 viruses continue to circulate in nature and threaten public health. Although several viral determinants and host factors that influence the virulence of HPAI H5N1 viruses in mammals have been identified, the detailed molecular mechanism remains poorl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Virol
Egile Nagusiak: Zhao, Dongming, Liang, Libin, Wang, Shuai, Nakao, Tomomi, Li, Yanbing, Liu, Liling, Guan, Yuntao, Fukuyama, Satoshi, Bu, Zhigao, Kawaoka, Yoshihiro, Chen, Hualan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2017
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355609/
https://ncbi.nlm.nih.gov/pubmed/28100622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02215-16
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