The PA Protein Directly Contributes to the Virulence of H5N1 Avian Influenza Viruses in Domestic Ducks

During their circulation in nature, H5N1 avian influenza viruses (AIVs) have acquired the ability to kill their natural hosts, wild birds and ducks. The genetic determinants for this increased virulence are largely unknown. In this study, we compared two genetically similar H5N1 AIVs, A/duck/Hubei/4...

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Hauptverfasser: Song, Jiasheng, Feng, Huapeng, Xu, Jing, Zhao, Dongming, Shi, Jianzhong, Li, Yanbing, Deng, Guohua, Jiang, Yongping, Li, Xuyong, Zhu, Pengyang, Guan, Yuntao, Bu, Zhigao, Kawaoka, Yoshihiro, Chen, Hualan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067757/
https://ncbi.nlm.nih.gov/pubmed/21177821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01975-10
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