The PA Protein Directly Contributes to the Virulence of H5N1 Avian Influenza Viruses in Domestic Ducks

During their circulation in nature, H5N1 avian influenza viruses (AIVs) have acquired the ability to kill their natural hosts, wild birds and ducks. The genetic determinants for this increased virulence are largely unknown. In this study, we compared two genetically similar H5N1 AIVs, A/duck/Hubei/4...

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Détails bibliographiques
Auteurs principaux: Song, Jiasheng, Feng, Huapeng, Xu, Jing, Zhao, Dongming, Shi, Jianzhong, Li, Yanbing, Deng, Guohua, Jiang, Yongping, Li, Xuyong, Zhu, Pengyang, Guan, Yuntao, Bu, Zhigao, Kawaoka, Yoshihiro, Chen, Hualan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2011
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067757/
https://ncbi.nlm.nih.gov/pubmed/21177821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01975-10
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