Molecular Determinants of Virulence and Stability of a Reporter-Expressing H5N1 Influenza A Virus

We previously reported that an H5N1 virus carrying the Venus reporter gene, which was inserted into the NS gene segment from the A/Puerto Rico/8/1934(H1N1) virus (Venus-H5N1 virus), became more lethal to mice, and the reporter gene was stably maintained after mouse adaptation compared with the wild-...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhao, Dongming, Fukuyama, Satoshi, Yamada, Shinya, Lopes, Tiago J. S., Maemura, Tadashi, Katsura, Hiroaki, Ozawa, Makoto, Watanabe, Shinji, Neumann, Gabriele, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645634/
https://ncbi.nlm.nih.gov/pubmed/26339046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01886-15
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