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Amino acid changes in PB2 and HA affect the growth of a recombinant influenza virus expressing a fluorescent reporter protein

Influenza viruses that express reporter proteins are useful tools, but are often attenuated. Recently, we found that an influenza virus encoding the Venus fluorescent protein acquired two mutations in its PB2 and HA proteins upon mouse adaptation. Here, we demonstrate that the enhanced viral replica...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Katsura, Hiroaki, Fukuyama, Satoshi, Watanabe, Shinji, Ozawa, Makoto, Neumann, Gabriele, Kawaoka, Yoshihiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742795/
https://ncbi.nlm.nih.gov/pubmed/26847414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19933
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