Virulence-Affecting Amino Acid Changes in the PA Protein of H7N9 Influenza A Viruses

Novel avian-origin influenza A(H7N9) viruses were first reported to infect humans in March 2013. To date, 143 human cases, including 45 deaths, have been recorded. By using sequence comparisons and phylogenetic and ancestral inference analyses, we identified several distinct amino acids in the A(H7N...

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Bibliografiske detaljer
Main Authors: Yamayoshi, Seiya, Yamada, Shinya, Fukuyama, Satoshi, Murakami, Shin, Zhao, Dongming, Uraki, Ryuta, Watanabe, Tokiko, Tomita, Yuriko, Macken, Catherine, Neumann, Gabriele, Kawaoka, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957961/
https://ncbi.nlm.nih.gov/pubmed/24371069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03155-13
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