Virulence-Affecting Amino Acid Changes in the PA Protein of H7N9 Influenza A Viruses

Novel avian-origin influenza A(H7N9) viruses were first reported to infect humans in March 2013. To date, 143 human cases, including 45 deaths, have been recorded. By using sequence comparisons and phylogenetic and ancestral inference analyses, we identified several distinct amino acids in the A(H7N...

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Main Authors: Yamayoshi, Seiya, Yamada, Shinya, Fukuyama, Satoshi, Murakami, Shin, Zhao, Dongming, Uraki, Ryuta, Watanabe, Tokiko, Tomita, Yuriko, Macken, Catherine, Neumann, Gabriele, Kawaoka, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957961/
https://ncbi.nlm.nih.gov/pubmed/24371069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03155-13
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