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Identification of novel amino acid residues of influenza virus PA-X that are important for PA-X shutoff activity by using yeast
The influenza A virus protein PA-X comprises an N-terminal PA region and a C-terminal PA-X-specific region. PA-X suppresses host gene expression, termed shutoff, via mRNA cleavage. Although the endonuclease active site in the N-terminal PA region of PA-X and basic amino acids in the C-terminal PA-X-...
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| Veröffentlicht in: | Virology |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6296753/ https://ncbi.nlm.nih.gov/pubmed/29331676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.01.004 |
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