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Mapping of a Region of the PA-X Protein of Influenza A Virus That Is Important for Its Shutoff Activity
Influenza A virus PA-X comprises an N-terminal PA endonuclease domain and a C-terminal PA-X-specific domain. PA-X reduces host and viral mRNA accumulation via its endonuclease function. Here, we found that the N-terminal 15 amino acids, particularly six basic amino acids, in the C-terminal PA-X-spec...
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| Publicado no: | J Virol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4524237/ https://ncbi.nlm.nih.gov/pubmed/26041295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01132-15 |
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