Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth

Mitochondria can be involved in regulating cellular stress response to hypoxia and tumor growth, but little is known about that mechanistic relationship. Here, we show that mitochondrial deficiency severely retards tumor xenograft growth with impairing hypoxic induction of HIF-1 transcriptional acti...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Koido, Masaru, Haga, Naomi, Furuno, Aki, Tsukahara, Satomi, Sakurai, Junko, Tani, Yuri, Sato, Shigeo, Tomida, Akihiro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2017
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355308/
https://ncbi.nlm.nih.gov/pubmed/28060746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14415
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