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Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth
Mitochondria can be involved in regulating cellular stress response to hypoxia and tumor growth, but little is known about that mechanistic relationship. Here, we show that mitochondrial deficiency severely retards tumor xenograft growth with impairing hypoxic induction of HIF-1 transcriptional acti...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5355308/ https://ncbi.nlm.nih.gov/pubmed/28060746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14415 |
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