Mitochondrial deficiency impairs hypoxic induction of HIF-1 transcriptional activity and retards tumor growth

Mitochondria can be involved in regulating cellular stress response to hypoxia and tumor growth, but little is known about that mechanistic relationship. Here, we show that mitochondrial deficiency severely retards tumor xenograft growth with impairing hypoxic induction of HIF-1 transcriptional acti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Koido, Masaru, Haga, Naomi, Furuno, Aki, Tsukahara, Satomi, Sakurai, Junko, Tani, Yuri, Sato, Shigeo, Tomida, Akihiro
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2017
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355308/
https://ncbi.nlm.nih.gov/pubmed/28060746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14415
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