Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

Developmental transcription programs are epigenetically regulated by the competing actions of polycomb and trithorax (TrxG) protein complexes, which repress and activate genes, respectively. Ewing sarcoma is a developmental tumor that is associated with widespread de-regulation of developmental tran...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Svoboda, Laurie K., Bailey, Natashay, Van Noord, Raelene A., Krook, Melanie A., Harris, Ashley, Cramer, Cassondra, Jasman, Brooke, Patel, Rajiv M., Thomas, Dafydd, Borkin, Dmitry, Cierpicki, Tomasz, Grembecka, Jolanta, Lawlor, Elizabeth R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352134/
https://ncbi.nlm.nih.gov/pubmed/27888797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13444
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