Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

Developmental transcription programs are epigenetically regulated by the competing actions of polycomb and trithorax (TrxG) protein complexes, which repress and activate genes, respectively. Ewing sarcoma is a developmental tumor that is associated with widespread de-regulation of developmental tran...

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Udgivet i:Oncotarget
Main Authors: Svoboda, Laurie K., Bailey, Natashay, Van Noord, Raelene A., Krook, Melanie A., Harris, Ashley, Cramer, Cassondra, Jasman, Brooke, Patel, Rajiv M., Thomas, Dafydd, Borkin, Dmitry, Cierpicki, Tomasz, Grembecka, Jolanta, Lawlor, Elizabeth R.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352134/
https://ncbi.nlm.nih.gov/pubmed/27888797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13444
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