Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

Developmental transcription programs are epigenetically regulated by the competing actions of polycomb and trithorax (TrxG) protein complexes, which repress and activate genes, respectively. Ewing sarcoma is a developmental tumor that is associated with widespread de-regulation of developmental tran...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Svoboda, Laurie K., Bailey, Natashay, Van Noord, Raelene A., Krook, Melanie A., Harris, Ashley, Cramer, Cassondra, Jasman, Brooke, Patel, Rajiv M., Thomas, Dafydd, Borkin, Dmitry, Cierpicki, Tomasz, Grembecka, Jolanta, Lawlor, Elizabeth R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352134/
https://ncbi.nlm.nih.gov/pubmed/27888797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13444
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