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Chemical approaches to targeted protein degradation through modulation of the ubiquitin–proteasome pathway

Manipulation of the ubiquitin–proteasome system to achieve targeted degradation of proteins within cells using chemical tools and drugs has the potential to transform pharmacological and therapeutic approaches in cancer and other diseases. An increased understanding of the molecular mechanism of tha...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Biochem J
Asıl Yazarlar: Collins, Ian, Wang, Hannah, Caldwell, John J., Chopra, Raj
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5350610/
https://ncbi.nlm.nih.gov/pubmed/28298557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160762
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