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Method for targeting protein destruction by using a ubiquitin-independent, proteasome-mediated degradation pathway

With the euchromatic portion of several mammalian genomes now sequenced, emphasis has turned to ascertaining the functions of gene products. A method for targeting destruction of selected proteins in mammalian cells is described, based on the ubiquitin-independent mechanism by which ornithine decarb...

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Autori principali: Matsuzawa, Shu-ichi, Cuddy, Michael, Fukushima, Toru, Reed, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257734/
https://ncbi.nlm.nih.gov/pubmed/16219697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507512102
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