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Activin-β(C) modulates cachexia by repressing the ubiquitin-proteasome and autophagic degradation pathways

BACKGROUND: Cancer-associated cachexia and muscle wasting are considered key determinants of cancer-related death and reduction in the quality of life of cancer patients. A crucial link has been established between activin signaling and skeletal muscle atrophy-hypertrophy. We previously showed that...

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Publicat a:J Cachexia Sarcopenia Muscle
Autors principals: Marino, Francesco Elia, Risbridger, Gail, Gold, Elspeth
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4670746/
https://ncbi.nlm.nih.gov/pubmed/26673867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12031
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