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Pathway choice between proteasomal and autophagic degradation

Efficient degradation of abnormal or aggregated proteins is crucial to protect the cell against proteotoxic stress. Selective targeting and disposal of such proteins usually occurs in a ubiquitin-dependent manner by proteasomes and macroautophagy/autophagy. Whereas proteasomes are efficient in degra...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Lu, Kefeng, den Brave, Fabian, Jentsch, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965392/
https://ncbi.nlm.nih.gov/pubmed/28813181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2017.1358851
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