In vivo evaluation of [(18)F]FECIMBI-36, an agonist 5-HT(2A/2C) receptor PET radioligand in nonhuman primate

We recently reported the radiosynthesis and in vitro evaluation of [(18)F]-2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-(2-fluoroethoxy)benzyl)ethanamine, ([(18)F]FECIMBI-36) or ([(18)F]1), an agonist radioligand for 5HT(2A/2C) receptors in postmortem samples of human brain. Herein we describe the in vivo e...

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Publicat a:Bioorg Med Chem Lett
Autors principals: Prabhakaran, Jaya, Sai, Kiran Kumar Solingapuram, Zanderigo, Francesca, Rubin-Falcone, Harry, Jorgensen, Matthew J., Kaplan, Jay R., Tooke, Katharine I., Mintz, Akiva, Mann, J. John, Dileep Kumar, J. S.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348621/
https://ncbi.nlm.nih.gov/pubmed/27889455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.11.043
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