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Radiosynthesis and evaluation of [(11)C]CMP, a high affinity GSK3 ligand
Dysfunction of GSK3 is implicated in the etiology of many brain, inflammatory, cardiac diseases, and cancer. PET imaging would enable in vivo detection and quantification of GSK3 and can impact the choice of therapy, allow non-invasive monitoring of disease progression and treatment effects. In this...
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| Veröffentlicht in: | Bioorg Med Chem Lett |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7703381/ https://ncbi.nlm.nih.gov/pubmed/30709652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.01.033 |
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