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Radiosynthesis and Evaluation of [(11)C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules
[Image: see text] Microtubules (MTs) are highly abundant throughout the cytoskeleton, and their dysfunction is implicated in the pathogenesis of malignancies, various neurodegenerative disorders, and brain injuries. Validated radiotracers reported so far for MTs are [(11)C]paclitaxel, [(18)F]fluorop...
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| Gepubliceerd in: | ACS Med Chem Lett |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Chemical
Society
2018
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| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5949725/ https://ncbi.nlm.nih.gov/pubmed/29795758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.8b00060 |
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