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Radiosynthesis and in Vivo Evaluation of [(11)C]A1070722, a High Affinity GSK-3 PET Tracer in Primate Brain
Dysfunction of glycogen synthase kinase 3 (GSK-3) is implicated in the etiology of Alzheimer’s disease, Parkinson’s disease, diabetes, pain, and cancer. A radiotracer for functional positron emission tomography (PET) imaging could be used to study the kinase in brain disorders and to facilitate the...
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| Gepubliceerd in: | ACS Chem Neurosci |
|---|---|
| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5559324/ https://ncbi.nlm.nih.gov/pubmed/28485573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00376 |
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