Synthesis and in vitro evaluation of [(18)F]FECIMBI-36: A potential agonist PET ligand for 5-HT(2A/2C) receptors

Radiosynthesis and in vitro evaluation of [(18)F]-2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-(2-fluoroethoxy)benzyl)ethanamine, ([(18)F]FECIMBI-36) or ([(18)F]1), a potential agonist PET imaging agent for 5-HT(2A/2C) receptors is described. Syntheses of reference standard 1 and the corresponding des-fluor...

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Bibliografski detalji
Izdano u:Bioorg Med Chem Lett
Glavni autori: Prabhakaran, Jaya, Underwood, Mark D., Dileep Kumar, J. S., Simpson, Norman R., Kassir, Suham A., Bakalian, Mihran J., Mann, J. John, Arango, Victoria
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4816213/
https://ncbi.nlm.nih.gov/pubmed/26253634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.07.034
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