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The role of calpains in ventilator-induced diaphragm atrophy

BACKGROUND: Controlled mechanical ventilation (CMV) is associated with diaphragm dysfunction. Dysfunction results from muscle atrophy and injury of diaphragm muscle fibers. Enhanced proteolysis and reduced protein synthesis play an important role in the development of atrophy. The current study is t...

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Bibliografische gegevens
Gepubliceerd in:Intensive Care Med Exp
Hoofdauteurs: Zhu, Xiaoping, van Hees, Hieronymus W. H., Heunks, Leo, Wang, Feifei, Shao, Lei, Huang, Jiaru, Shi, Lei, Ma, Shaolin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348482/
https://ncbi.nlm.nih.gov/pubmed/28290154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0127-4
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