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The role of calpains in ventilator-induced diaphragm atrophy

BACKGROUND: Controlled mechanical ventilation (CMV) is associated with diaphragm dysfunction. Dysfunction results from muscle atrophy and injury of diaphragm muscle fibers. Enhanced proteolysis and reduced protein synthesis play an important role in the development of atrophy. The current study is t...

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Podrobná bibliografie
Vydáno v:Intensive Care Med Exp
Hlavní autoři: Zhu, Xiaoping, van Hees, Hieronymus W. H., Heunks, Leo, Wang, Feifei, Shao, Lei, Huang, Jiaru, Shi, Lei, Ma, Shaolin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348482/
https://ncbi.nlm.nih.gov/pubmed/28290154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0127-4
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