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Hypercapnia attenuates ventilator-induced diaphragm atrophy and modulates dysfunction

INTRODUCTION: Diaphragm weakness induced by prolonged mechanical ventilation may contribute to difficult weaning from the ventilator. Hypercapnia is an accepted side effect of low tidal volume mechanical ventilation, but the effects of hypercapnia on respiratory muscle function are largely unknown....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schellekens, Willem-Jan M, van Hees, Hieronymus WH, Kox, Matthijs, Linkels, Marianne, Acuña, Gilberto L Andrade, Dekhuijzen, PN Richard, Scheffer, Gert Jan, van der Hoeven, Johannes G, Heunks, Leo MA
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056638/
https://ncbi.nlm.nih.gov/pubmed/24506836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13719
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