Hypercapnia attenuates ventilator-induced diaphragm atrophy and modulates dysfunction

INTRODUCTION: Diaphragm weakness induced by prolonged mechanical ventilation may contribute to difficult weaning from the ventilator. Hypercapnia is an accepted side effect of low tidal volume mechanical ventilation, but the effects of hypercapnia on respiratory muscle function are largely unknown....

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Detalhes bibliográficos
Main Authors: Schellekens, Willem-Jan M, van Hees, Hieronymus WH, Kox, Matthijs, Linkels, Marianne, Acuña, Gilberto L Andrade, Dekhuijzen, PN Richard, Scheffer, Gert Jan, van der Hoeven, Johannes G, Heunks, Leo MA
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056638/
https://ncbi.nlm.nih.gov/pubmed/24506836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13719
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