Levosimendan affects oxidative and inflammatory pathways in the diaphragm of ventilated endotoxemic mice

INTRODUCTION: Controlled mechanical ventilation and endotoxemia are associated with diaphragm muscle atrophy and dysfunction. Oxidative stress and activation of inflammatory pathways are involved in the pathogenesis of diaphragmatic dysfunction. Levosimendan, a cardiac inotrope, has been reported to...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Schellekens, Willem-Jan M, van Hees, Hieronymus WH, Linkels, Marianne, Dekhuijzen, PN Richard, Scheffer, Gert Jan, van der Hoeven, Johannes G, Heunks, Leo MA
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355991/
https://ncbi.nlm.nih.gov/pubmed/25888356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0798-8
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