Titin and diaphragm dysfunction in mechanically ventilated rats

PURPOSE: Diaphragm weakness induced by mechanical ventilation may contribute to difficult weaning from the ventilator. For optimal force generation the muscle proteins myosin and titin are indispensable. The present study investigated if myosin and titin loss or dysfunction are involved in mechanica...

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Main Authors: van Hees, Hieronymus W. H., Schellekens, Willem-Jan M., Andrade Acuña, Gilberto L., Linkels, Marianne, Hafmans, Theo, Ottenheijm, Coen A. C., Granzier, Henk L., Scheffer, Gert-Jan, van der Hoeven, Johannes G., Dekhuijzen, P. N. Richard, Heunks, Leo M. A.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2012
主題:
Experimental
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308006/
https://ncbi.nlm.nih.gov/pubmed/22327561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-012-2504-5
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