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Titin-based mechanosensing and signaling: role in diaphragm atrophy during unloading?

The diaphragm, the main muscle of inspiration, is constantly subjected to mechanical loading. One of the very few occasions during which diaphragm loading is arrested is during controlled mechanical ventilation in the intensive care unit. Recent animal studies indicate that the diaphragm is extremel...

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Main Authors: Ottenheijm, Coen A. C., van Hees, Hieronymus W. H., Heunks, Leo M. A., Granzier, Henk
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043808/
https://ncbi.nlm.nih.gov/pubmed/21075826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00288.2010
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