The role of calpains in ventilator-induced diaphragm atrophy

BACKGROUND: Controlled mechanical ventilation (CMV) is associated with diaphragm dysfunction. Dysfunction results from muscle atrophy and injury of diaphragm muscle fibers. Enhanced proteolysis and reduced protein synthesis play an important role in the development of atrophy. The current study is t...

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Bibliografiske detaljer
Udgivet i:Intensive Care Med Exp
Main Authors: Zhu, Xiaoping, van Hees, Hieronymus W. H., Heunks, Leo, Wang, Feifei, Shao, Lei, Huang, Jiaru, Shi, Lei, Ma, Shaolin
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348482/
https://ncbi.nlm.nih.gov/pubmed/28290154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-017-0127-4
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