Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response

The innate immune system senses RNA viruses by pattern recognition receptors (PRRs) and protects the host from virus infection. PRRs mediate the production of immune modulatory factors and direct the elimination of RNA viruses. Here, we show a unique PRR that mediates antiviral response. Tetrachloro...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kozaki, Tatsuya, Komano, Jun, Kanbayashi, Daiki, Takahama, Michihiro, Misawa, Takuma, Satoh, Takashi, Takeuchi, Osamu, Kawai, Taro, Shimizu, Shigeomi, Matsuura, Yoshiharu, Akira, Shizuo, Saitoh, Tatsuya
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347618/
https://ncbi.nlm.nih.gov/pubmed/28213497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621508114
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