Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response

The innate immune system senses RNA viruses by pattern recognition receptors (PRRs) and protects the host from virus infection. PRRs mediate the production of immune modulatory factors and direct the elimination of RNA viruses. Here, we show a unique PRR that mediates antiviral response. Tetrachloro...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Kozaki, Tatsuya, Komano, Jun, Kanbayashi, Daiki, Takahama, Michihiro, Misawa, Takuma, Satoh, Takashi, Takeuchi, Osamu, Kawai, Taro, Shimizu, Shigeomi, Matsuura, Yoshiharu, Akira, Shizuo, Saitoh, Tatsuya
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347618/
https://ncbi.nlm.nih.gov/pubmed/28213497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621508114
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