Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response

The innate immune system senses RNA viruses by pattern recognition receptors (PRRs) and protects the host from virus infection. PRRs mediate the production of immune modulatory factors and direct the elimination of RNA viruses. Here, we show a unique PRR that mediates antiviral response. Tetrachloro...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kozaki, Tatsuya, Komano, Jun, Kanbayashi, Daiki, Takahama, Michihiro, Misawa, Takuma, Satoh, Takashi, Takeuchi, Osamu, Kawai, Taro, Shimizu, Shigeomi, Matsuura, Yoshiharu, Akira, Shizuo, Saitoh, Tatsuya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347618/
https://ncbi.nlm.nih.gov/pubmed/28213497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621508114
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