Enhanced TLR-mediated NF-IL6–dependent gene expression by Trib1 deficiency

Toll-like receptors (TLRs) recognize a variety of microbial components and mediate downstream signal transduction pathways that culminate in the activation of nuclear factor κB (NF-κB) and mitogen-activated protein (MAP) kinases. Trib1 is reportedly involved in the regulation of NF-κB and MAP kinase...

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Autors principals: Yamamoto, Masahiro, Uematsu, Satoshi, Okamoto, Toru, Matsuura, Yoshiharu, Sato, Shintaro, Kumar, Himanshu, Satoh, Takashi, Saitoh, Tatsuya, Takeda, Kiyoshi, Ishii, Ken J., Takeuchi, Osamu, Kawai, Taro, Akira, Shizuo
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118688/
https://ncbi.nlm.nih.gov/pubmed/17724128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070183
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