Innate Immune Response Induced by Baculovirus Attenuates Transgene Expression in Mammalian Cells

The baculovirus Autographa californica nucleopolyhedrovirus (AcNPV) has been widely used to achieve a high level of foreign gene expression in insect cells, as well as for efficient gene transduction into mammalian cells without any replication. In addition to permitting efficient gene delivery, bac...

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Detalhes bibliográficos
Main Authors: Ono, Chikako, Ninomiya, Akinori, Yamamoto, Satomi, Abe, Takayuki, Wen, Xiauyu, Fukuhara, Takasuke, Sasai, Miwa, Yamamoto, Masahiro, Saitoh, Tatsuya, Satoh, Takashi, Kawai, Taro, Ishii, Ken J., Akira, Shizuo, Okamoto, Toru, Matsuura, Yoshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Gene Delivery
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911546/
https://ncbi.nlm.nih.gov/pubmed/24335288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03055-13
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