Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response

The innate immune system senses RNA viruses by pattern recognition receptors (PRRs) and protects the host from virus infection. PRRs mediate the production of immune modulatory factors and direct the elimination of RNA viruses. Here, we show a unique PRR that mediates antiviral response. Tetrachloro...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Kozaki, Tatsuya, Komano, Jun, Kanbayashi, Daiki, Takahama, Michihiro, Misawa, Takuma, Satoh, Takashi, Takeuchi, Osamu, Kawai, Taro, Shimizu, Shigeomi, Matsuura, Yoshiharu, Akira, Shizuo, Saitoh, Tatsuya
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2017
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347618/
https://ncbi.nlm.nih.gov/pubmed/28213497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621508114
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