The RAB2B-GARIL5 complex promotes cytosolic DNA-induced innate immune responses

Cyclic GMP-AMP synthase (cGAS) is a cytosolic DNA sensor that induces the IFN antiviral response. However, the regulatory mechanisms that mediate cGAS-triggered signaling have not been fully explored. Here, we show the involvement of a small GTPase RAB2B and its effector protein Golgi-associated RAB...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Takahama, Michihiro, Fukuda, Mitsunori, Ohbayashi, Norihiko, Kozaki, Tatsuya, Misawa, Takuma, Okamoto, Toru, Matsuura, Yoshiharu, Akira, Shizuo, Saitoh, Tatsuya
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5614515/
https://ncbi.nlm.nih.gov/pubmed/28930687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.085
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker