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Angptl4 does not control hyperglucagonemia or α-cell hyperplasia following glucagon receptor inhibition
Genetic disruption or pharmacologic inhibition of glucagon signaling effectively lowers blood glucose but results in compensatory glucagon hypersecretion involving expansion of pancreatic α-cell mass. Ben-Zvi et al. recently reported that angiopoietin-like protein 4 (Angptl4) links glucagon receptor...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347591/ https://ncbi.nlm.nih.gov/pubmed/28143927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620989114 |
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