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ANGPTL8 (Betatrophin) Does Not Control Pancreatic Beta Cell Expansion

Yi et al. (2013) recently reported that angiopoietin-like protein 8 (ANGPTL8) was the long-sought “betatrophin” that could control pancreatic beta cell proliferation. However, studies of Angptl8(−/−) mice revealed profound reduction of triglyceride levels, but no abnormalities in glucose homeostasis...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell
Hauptverfasser: Gusarova, Viktoria, Alexa, Corey A., Na, Erqian, Stevis, Panayiotis E., Xin, Yurong, Bonner-Weir, Susan, Cohen, Jonathan C., Hobbs, Helen H., Murphy, Andrew J., Yancopoulos, George D., Gromada, Jesper
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4243040/
https://ncbi.nlm.nih.gov/pubmed/25417115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.027
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